HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Cyclopropylaniline → (3-Cyclopropyl-phenyl)-(6-nitro-4H-benzo[d][1,3]oxazin-2-yl)-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Cyclopropylaniline | HCID 12032139 | — |
| Reactant | tert-Butyl-(2-isothiocyanato-5-nitro-benzyloxy)-dimethyl-silane | HCID 46855450 | — |
| Product | (3-Cyclopropyl-phenyl)-(6-nitro-4H-benzo[d][1,3]oxazin-2-yl)-amine | HCID 67277073 | 74% |
Reaction Steps
Prepared from tert-butyl-(2-isothiocyanato-5-nitro-benzyloxy)-dimethyl-silane (Example C1) (5.8 g, 18 mmol) and 3-cyclopropyl-phenylamine (2.5 g, 19 mmol) according to the procedure described for Example 1. Obtained the title compound as a yellow foam (4.1 g, 74%), MS (ISP) m/e=310.5 [(M+H)+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08163740B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-f1f456346a0246368e05ce5ef33221b9 |
| Source note | uspto-grants-2012_04 |