Isopropyl isocyanate → HCID 178457914, compound

HRID 1695698Notes

Reaction equation

HRID 1695698 reaction equation
[CH:1]1([NH:9][C:10]2[O:11][CH2:12][C:13]3[CH:19]=[C:18]([NH2:20])[CH:17]=[CH:16][C:14]=3[N:15]=2)[CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]C1.[CH:21]([N:24]=[C:25]=[O:26])([CH3:23])[CH3:22]>>[CH:1]1([NH:9][C:10]2[O:11][CH2:12][C:13]3[CH:19]=[C:18]([NH:20][C:25]([NH:24][CH:21]([CH3:23])[CH3:22])=[O:26])[CH:17]=[CH:16][C:14]=3[N:15]=2)[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8]1

Participants

3

Reactant 2

HCID 61277Isopropyl isocyanateHCID 178507251HCID 178507251, compound

Product 1

HCID 178457914HCID 178457914, compoundYield 20%

Procedure

Prepared from N2-cyclooctyl-4H-benzo[d][1,3]oxazine-2,6-diamine (210 mg, 0.81 mmol) and isopropyl isocyanate (76 mg, 0.89 mmol) according to the procedure described for Example 16. Obtained the title compound as an off-white foam (55 mg, 20%), MS (ISP) m/e=345.3 [(M+H)+].

Sources & evidence

ORD record
ord-237cac963d344f51afb4fb2036e44d3a
Source dataset
uspto-grants-2012_04
Patent number
US08163740B2

Reaction notes

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