Diisopropylethylamine → HCID 178494600, compound

Participants

Reaction Steps

Prepared from 2-chloro-N-[2-((R)-indan-1-ylamino)-4H-benzo[d][1,3]oxazin-6-yl]-acetamide (Example 3 step A) (100 mg, 0.281 mmol), the above described (2SR,6SR)-2,6-bis-methoxymethyl-1-methyl-piperazine hydrochloride (69.5 mg, 0.309 mmol) and diisopropylethyl amine (144 ul, 0.843 mmol) in acetonitrile (2 ml) according to the procedure described for Example 3 step B. Obtained the title compound as a light yellow solid (15 mg, 11%), MS (ISP) m/e=508.4 [(M+H)+].

Provenance & Evidence