Tetrahydrofuran → HCID 76550431, compound

HRID 169590Notes

Reaction equation

[C:19]([Si:20]([CH3:21])([CH3:22])[O:24][CH2:25][CH2:26][CH2:27][CH:28]([C:29](=[O:30])[NH:31][c:32]1[n:33][cH:34][c:35]([C:38]#[N:39])[cH:36][cH:37]1)[O:40][c:41]1[c:42]2[c:43]([n:44][cH:45][n:46]1)[n:47](-[c:50]1[n:51][cH:52][cH:53][cH:54][c:55]1[Cl:56])[n:48][cH:49]2)([CH3:23])([CH3:57])[CH3:58].[CH2:59]1[O:60][CH2:61][CH2:62][CH2:63]1.[CH3:2][CH2:3][CH2:4][CH2:5][N+:6]([CH2:7][CH2:8][CH2:9][CH3:10])([CH2:11][CH2:12][CH2:13][CH3:14])[CH2:15][CH2:16][CH2:17][CH3:18].[F-:1]>>[OH:24][CH2:25][CH2:26][CH2:27][CH:28]([C:29](=[O:30])[NH:31][c:32]1[n:33][cH:34][c:35]([C:38]#[N:39])[cH:36][cH:37]1)[O:40][c:41]1[c:42]2[c:43]([n:44][cH:45][n:46]1)[n:47](-[c:50]1[n:51][cH:52][cH:53][cH:54][c:55]1[Cl:56])[n:48][cH:49]2

Participants

Reactant 4

HCID 8028Tetrahydrofuran

HCID 16028Tetrabutylammonium

HCID 28179Fluoride Ion

HCID 765505105-[tert-butyl(dimethyl)silyl]oxy-2-[1-(3-chloro-2-pyridinyl)pyrazolo[5,4-d]pyrimidin-4-yl]oxy-N-(5-cyano-2-pyridinyl)pentanamide

Product 1

HCID 76550431HCID 76550431, compound

Sources & evidence

ORD record: ord-d211482d487346a2b328b178279839fd
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

Reaction notes

Loading…