Stannous chloride dihydrate → HCID 67272092, compound

Participants

Reaction Steps

To a solution of 1H-indazol-6-ylamine (20 g, 153 mmol) in conc. HCl (50 mL) was added an aqueous solution (50 mL) of NaNO2 (19 g, 158 mmol) at 0° C. and the resulting mixture was stirred for 1 h. A solution of SnCl2.2H2O (90 g, 306 mmol) in conc. HCl (70 mL) pre-cooled to 0° C. was then added, and the mixture stirred for 2 h at RT. The precipitate was filtered and washed with Et2O to yield (1H-indazol-6-yl)-hydrazine hydrochloride as a yellow solid, which was used without further purification.

Provenance & Evidence