Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | Ethyl 2,6-diaminopyridine-4-carboxylate | HCID 57357157 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 67274029 | HCID 67274029 | — |
Reaction Steps
A mixture of 0.270 g 2,6-diaminoisonicotinic acid ethyl ester and 5 ml of a 2M solution of methylamine in methanol was stirred at 70° C. for 24 h. The solvent were evaporated and the residue was triturated with ethyl acetate to yield 0.214 g of the title compound as light brown solid. MS (ISP) M+H+=167.4
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08163778B2 |
|---|
| Source dataset | uspto-grants-2012_04 |
|---|
| ORD ID | ord-aea08b56640f48c29b81bec149bfe27c |
|---|
| Source note | uspto-grants-2012_04 |
|---|
