Ammonia → HCID 67273710, compound

HRID 1696780Notes

Reaction equation

HRID 1696780 reaction equation
C[O:2][C:3]([C:5]1[CH:10]=[C:9]([S:11][CH3:12])[CH:8]=[C:7]([NH2:13])[N:6]=1)=O.[NH3:14]>>[NH2:13][C:7]1[N:6]=[C:5]([C:3]([NH2:14])=[O:2])[CH:10]=[C:9]([S:11][CH3:12])[CH:8]=1

Participants

3

Reactant 2

HCID 222AmmoniaHCID 67274196HCID 67274196, compound

Product 1

HCID 67273710HCID 67273710, compound

Procedure

A mixture of 0.099 g 6-amino-4-methylsulfanyl-pyridine-2-carboxylic acid methyl ester in 4 ml 25% aqueous ammonia was stirred at room temperature for 24 h. The solid was collected by filtration washed with water and dried to constant weight to yield 0.070 g of the title compound as white crystals melting at 158-159° C.

Workup

  1. filtrationThe solid was collected by filtration
  2. washwashed with water
  3. customdried to constant weight

Sources & evidence

ORD record
ord-1290526803ca448985a184b120916241
Source dataset
uspto-grants-2012_04
Patent number
US08163778B2

Reaction notes

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