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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1696817Generated: November 2, 2026

Hydrochloric Acid → HCID 66618519, compound

https://huagongshe.com/reaction/1696817

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 42053071HCID 42053071—
SolventDichloromethaneHCID 6344—
ProductHCID 66618519HCID 6661851992%

Reaction Steps

To a cooled solution of (S)-3-(4-fluoro-phenylcarbamoyl)-piperidine-1-carboxylic acid tert-butyl ester (0.34 g, 1.05 mmol) in dichloromethane (5 mL) was added dropwise 5.2 mL of HCl 4N (dioxane solution) and the solution was stirred at R.T. for 45 min. The solvent was evaporated under reduced pressure to give the title compound as a white solid (0.252 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08163775B2
Source datasetuspto-grants-2012_04
ORD IDord-7d76c7afc99440ff99d35c0ee9ca928c
Source noteuspto-grants-2012_04