HCID 67275150, compound → HCID 67275775, compound

HRID 1696895Notes

Reaction equation

HRID 1696895 reaction equation
[N:1]1([C:5]2[N:14]=[C:13]3[C:8]([C:9](=[O:31])[C:10]([C:26]([O:28][CH2:29][CH3:30])=[O:27])=[CH:11][N:12]3CC3C=CC(OC)=CC=3OC)=[C:7]([CH3:32])[C:6]=2[F:33])[CH2:4][CH2:3][CH2:2]1>FC(F)(F)C(O)=O>[N:1]1([C:5]2[N:14]=[C:13]3[C:8]([C:9](=[O:31])[C:10]([C:26]([O:28][CH2:29][CH3:30])=[O:27])=[CH:11][NH:12]3)=[C:7]([CH3:32])[C:6]=2[F:33])[CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 1

HCID 67275150HCID 67275150, compound

Product 1

HCID 67275775HCID 67275775, compound

Reagents, catalysts & solvents 1

HCID 6422Trifluoroacetic acidSolvent

Procedure

A solution of Example 5A (267 mg) in trifluoroacetic acid (11 mL) was stirred at 40° C. for 3 hours and concentrated; and the concentrate was azeotroped with toluene.

Workup

  1. concentrationconcentrated
  2. customand the concentrate was azeotroped with toluene

Sources & evidence

ORD record
ord-9da0dd9a0b254ad087627bc5e404b74f
Source dataset
uspto-grants-2012_04
Patent number
US08163769B2

Reaction notes

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