HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 4-Sulfamoylbenzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 4-Formylbenzene-1-sulfonyl chloride | HCID 2759210 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4-Sulfamoylbenzaldehyde | HCID 151088 | — |
Reaction Steps
A solution of ammonia (0.5 M in 1,4-dioxane, 5 mL) was added to 4-formylbenzenesulfonyl chloride (0.5 g), followed by DCM (10 mL). The reaction mixture was stirred vigorously for 3 h at RT, then concentrated under reduced pressure. The crude residue was purified by flash chromatography to afford 4-formyl-benzenesulfonamide. MS=183.9 [M−H]−.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08163906B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-960ffd9a183d446db8976b3e3dbabf34 |
| Source note | uspto-grants-2012_04 |