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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1697498Generated: October 31, 2026

(S)-alpha-(Trifluoromethyl)benzyl alcohol → HCID 46946222, compound

https://huagongshe.com/reaction/1697498

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-alpha-(Trifluoromethyl)benzyl alcoholHCID 95556—
ReactantHCID 86646813HCID 86646813—
ProductHCID 46946222HCID 46946222—

Reaction Steps

L6. (2S,4R)-4-(2-chloro-benzenesulfonyl)-pyrrolidine-2-carboxylic acid cyanomethyl-amide hydrochloride from experiment K1 was reacted with 1-phenyl-2,2,2-trifluoroethanol as described in experiment L5 to give (2S,4R)-4-(2-chloro-benzenesulfonyl)-1-(2,2,2-trifluoro-1-phenyl-ethyl)-pyrrolidine-2-carboxylic acid cyanomethyl-amide as a white amorphous solid. MS: 486.2 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08163793B2
Source datasetuspto-grants-2012_04
ORD IDord-8eced90f9f724bc0af2f659c0dc2a5f7
Source noteuspto-grants-2012_04