HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methylpiperidine-4-carboxylic acid → HCID 46947016, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methylpiperidine-4-carboxylic acid | HCID 2736939 | — |
| Reactant | HCID 86646815 | HCID 86646815 | — |
| Product | HCID 46947016 | HCID 46947016 | — |
Reaction Steps
(2S,4R)-4-(2-trifluoromethyl-benzenesulfonyl)-pyrrolidine-2-carboxylic acid cyanomethyl-amide hydrochloride from experiment K2 was coupled with 1-methylpiperidine-4-carboxylic acid in analogy to experiment A1 to give (2S,4R)-1-(1-methyl-piperidine-4-carbonyl)-4-(2-trifluoromethyl-benzenesulfonyl)-pyrrolidine-2-carboxylic acid cyanomethyl-amide; salt with formic acid as a colorless oil. MS: 487.3 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08163793B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-a3cd7cd5021442ba937fc9cb4fc088f5 |
| Source note | uspto-grants-2012_04 |