HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,3,3-trifluoro-2-methylpropanal → HCID 46947018, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,3,3-trifluoro-2-methylpropanal | HCID 2782188 | — |
| Reactant | HCID 66770259 | HCID 66770259 | — |
| Product | HCID 46947018 | HCID 46947018 | — |
Reaction Steps
(2S,4R)-4-(2-chloro-benzenesulfonyl)-pyrrolidine-2-carboxylic acid (1-cyano-cyclopropyl)-amide hydrochloride from experiment K4 was reductively alkylated with rac-2-methyl-trifluoropropionaldehyde in analogy to experiment L3 to give (2S,4R)-4-(2-chloro-benzenesulfonyl)-1-(3,3,3-trifluoro-2-methyl-propyl)-pyrrolidine-2-carboxylic acid (1-cyano-cyclopropyl)-amide as a colorless solid. MS: 464.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08163793B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-553bc8e45ecc49cbaef6e9aeb425c5a3 |
| Source note | uspto-grants-2012_04 |