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HRID1697543

反应详情

EQUATION

反应方程式

HRID 1697543 的结构方程式

REACTANTS

反应物

2
结构：O=Cc1ccccc1
HCID240

Benzaldehyde

C7H6O

结构：Cl.N#CC1(NC(=O)[C@@H]2C[C@@H](S(=O)(=O)c3ccccc3C(F)(F)F)CN2)CC1
HCID66770594

未命名化合物

PRODUCTS

生成物

1
结构：N#CC1(NC(=O)[C@@H]2C[C@@H](S(=O)(=O)c3ccccc3C(F)(F)F)CN2Cc2ccccc2)CC1
HCID59543814

未命名化合物

PROCEDURE

实验过程

(2S,4R)-4-(2-trifluoromethyl-benzenesulfonyl)-pyrrolidine-2-carboxylic acid (1-cyano-cyclopropyl)-amide hydrochloride from experiment K5 was reductively aminated with benzaldehyde in analogy to experiment L3 to give (2S,4R)-1-benzyl-4-(2-trifluoromethyl-benzenesulfonyl)-pyrrolidine-2-carboxylic acid (1-cyano-cyclopropyl)-amide as a colorless oil. MS: 478.1 [M+H]+.