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HRID1697586

反应详情

EQUATION

反应方程式

HRID 1697586 的结构方程式

REACTANTS

反应物

2
反应SMILES：[Li+].[OH-]
HCID3939

Lithium hydroxide anhydrous

HLiO

反应SMILES：COC(=O)[C@@H]1C[C@@H](S(=O)(=O)c2ccccc2C(F)(F)F)CN1c1cc(C)[nH]n1
HCID66771974

未命名化合物

PRODUCTS

产物

1
反应SMILES：Cc1cc(N2C[C@H](S(=O)(=O)c3ccccc3C(F)(F)F)C[C@H]2C(=O)O)n[nH]1
HCID66772197

未命名化合物

PROCEDURE

实验过程

In analogy to the procedure described in example 253e, (2S,4R)-1-(5-methyl-1H-pyrazol-3-yl)-4-(2-trifluoromethyl-benzenesulfonyl)-pyrrolidine-2-carboxylic acid methyl ester was saponified in the presence of lithium hydroxide to give the title compound as yellow solid. MS (ESI): m/z=404.4 [M+H]+.