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HRID1697593

反应详情

EQUATION

反应方程式

HRID 1697593 的结构方程式

REACTANTS

反应物

2
结构：[Li+].[OH-]
HCID3939

Lithium hydroxide anhydrous

HLiO

结构：COC(=O)[C@@H]1C[C@@H](S(=O)(=O)c2ccccc2C(F)(F)F)CN1c1cc(C)nn1C1CCOCC1
HCID67278353

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cc(N2C[C@H](S(=O)(=O)c3ccccc3C(F)(F)F)C[C@H]2C(=O)O)n(C2CCOCC2)n1
HCID66770396

未命名化合物

PROCEDURE

实验过程

In analogy to the procedure described in example 253e, (2S,4R)-1-[5-methyl-2-(tetrahydro-pyran-4-yl)-2H-pyrazol-3-yl]-4-(2-trifluoromethyl-benzenesulfonyl)-pyrrolidine-2-carboxylic acid methyl ester was saponified in the presence of lithium hydroxide to give the title compound as orange oil.