反应详情

In analogy to the procedure described in example 306, (2S,4R)-4-(4-fluoro-2-trifluoromethyl-benzenesulfonyl)-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester (example 208 c) was treated with 2,2,2-trifluoroethanol and cesium carbonate to give a mixture of the title compound and starting material as yellow oil. MS (ESI): m/z=436.1 [M+H]+.

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