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HRID1697680

反应详情

EQUATION

反应方程式

HRID 1697680 的结构方程式

REACTANTS

反应物

2
结构：[Li+].[OH-]
HCID3939

Lithium hydroxide anhydrous

HLiO

结构：COC(=O)[C@@H]1C[C@@H](S(=O)(=O)c2ccccc2Cl)CN1c1nnc(C(F)(F)F)s1
HCID66772319

未命名化合物

PRODUCTS

生成物

1
结构：O=C(O)[C@@H]1C[C@@H](S(=O)(=O)c2ccccc2Cl)CN1c1nnc(C(F)(F)F)s1
HCID66772471

未命名化合物

PROCEDURE

实验过程

In analogy to the procedure described in example 253e, (2S,4R)-4-(2-chloro-benzenesulfonyl)-1-(5-trifluoromethyl-[1,3,4]thiadiazol-2-yl)-pyrrolidine-2-carboxylic acid methyl ester was saponified in the presence of lithium hydroxide to give the title compound as yellow oil. MS (ESI): m/z=442.0 [M+H]+.