HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Hydroxide → HCID 66771983, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | HCID 66772677 | HCID 66772677 | — |
| Product | HCID 66771983 | HCID 66771983 | — |
Reaction Steps
In analogy to the procedure described in example 253e, (2S,4R)-methyl 4-(2-chlorophenylsulfonyl)-1-(3-methyl-1-((1-methyl-1H-imidazol-5-yl)methyl)-1H-pyrazol-5-yl)pyrrolidine-2-carboxylate was saponified in the presence of lithium hydroxide to give the title compound as brown solid which was used in the next step without further purification. MS (ESI): m/z=462.1 [M−H]−.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08163793B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-b8827d90aa334702bbec9cc9b7b5e75e |
| Source note | uspto-grants-2012_04 |