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HRID1697781

反应详情

EQUATION

反应方程式

HRID 1697781 的结构方程式

REACTANTS

反应物

2
结构：Clc1nsc(Cl)n1
HCID2725055

3,5-dichloro-1,2,4-thiadiazole

C2Cl2N2S

结构：COC(=O)[C@@H]1C[C@@H](S(=O)(=O)c2ccccc2Cl)CN1
HCID66770749

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)[C@@H]1C[C@@H](S(=O)(=O)c2ccccc2Cl)CN1c1nc(Cl)ns1
HCID67278217

未命名化合物

PROCEDURE

实验过程

In analogy to the procedure described in example 335a, (2S,4R)-4-(2-chloro-benzenesulfonyl)-pyrrolidine-2-carboxylic acid methyl ester (example 253a) was reacted with 3,5-dichloro-[1,2,4]thiadiazole (CAS Reg. No. 2254-88-8) in a shaking reactor at 55° C. for 48 h to give the title compound as red oil. MS (ESI): m/z=422.0 [M+H]+.