Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1697920Generated: October 31, 2026

Isobutyl chloroformate → (S)-isobutyl 2-(4-(3-ethylureido)phenyl)-4-(3-methylmorpholino)-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxylate

https://huagongshe.com/reaction/1697920

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsobutyl chloroformateHCID 62365—
Reactant(S)-1-ethyl-3-(4-(4-(3-methylmorpholino)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-yl)phenyl)ureaHCID 46913569—
Product(S)-isobutyl 2-(4-(3-ethylureido)phenyl)-4-(3-methylmorpholino)-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxylateHCID 59239446—

Reaction Steps

Compound eu was prepared according to the procedure described in Example 5 by reacting (S)-1-ethyl-3-(4-(4-(3-methylmorpholino)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-yl)phenyl)urea with isobutyl chloroformate. LC-MS: m/z=+497 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08163763B2
Source datasetuspto-grants-2012_04
ORD IDord-54b935d05a3c4038a40ada701ddc158c
Source noteuspto-grants-2012_04