2-Bromopropane → HCID 59239620, compound

HRID 1697929Notes

Reaction equation

HRID 1697929 reaction equation
[CH3:1][C@@H:2]1[N:7]([C:8]2[C:9]3[CH2:24][CH2:23][NH:22][CH2:21][C:10]=3[N:11]=[C:12]([C:14]3[CH:15]=[N:16][C:17]([NH2:20])=[N:18][CH:19]=3)[N:13]=2)[CH2:6][CH2:5][O:4][CH2:3]1.[CH:25](Br)([CH3:27])[CH3:26]>>[CH:25]([N:22]1[CH2:23][CH2:24][C:9]2[C:8]([N:7]3[CH2:6][CH2:5][O:4][CH2:3][C@@H:2]3[CH3:1])=[N:13][C:12]([C:14]3[CH:15]=[N:16][C:17]([NH2:20])=[N:18][CH:19]=3)=[N:11][C:10]=2[CH2:21]1)([CH3:27])[CH3:26]

Participants

3

Reactant 2

HCID 63582-BromopropaneHCID 67176119HCID 67176119, compound

Product 1

HCID 59239620HCID 59239620, compound

Procedure

Compound fk was prepared according to the procedure described in Example 2 by reacting (S)-5-(4-(3-methylmorpholino)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl)pyrimidin-2-amine with isopropylbromide. LC-MS: m/z=+370 (M+H)−.

Workup

  1. customCompound fk was prepared

Sources & evidence

ORD record
ord-0a8a465dafb247ebb5758915c14ba3c3
Source dataset
uspto-grants-2012_04
Patent number
US08163763B2

Reaction notes

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