Dimethyl Sulfone → HCID 66727152, compound

HRID 1698253Notes

Reaction equation

HRID 1698253 reaction equation
Br[C:2]1[CH:7]=[C:6]([C:8](=[O:11])[CH2:9][CH3:10])[CH:5]=[CH:4][N:3]=1.[CH3:12][S:13](C)(=[O:15])=[O:14]>>[CH3:12][S:13]([C:2]1[CH:7]=[C:6]([C:8](=[O:11])[CH2:9][CH3:10])[CH:5]=[CH:4][N:3]=1)(=[O:15])=[O:14]

Participants

3

Reactant 2

HCID 6213Dimethyl SulfoneHCID 592773031-(2-Bromopyridin-4-yl)propan-1-one

Product 1

HCID 66727152HCID 66727152, compound

Procedure

Alternatively, (1-(2-bromo-pyridin-4-yl)-propan-1-one could be converted to the corresponding methyl sulfone via the above procedure to afford 1-(2-methanesulfonyl-pyridin-4-yl)-propan-1-one. 1-(2-Methanesulfonyl-pyridin-4-yl)-propan-1-one can be converted to the title compound by methods described in example 82.

Sources & evidence

ORD record
ord-97c62555eb344261b323d9073f806b0e
Source dataset
uspto-grants-2012_04
Patent number
US08163918B2

Reaction notes

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