Ammonium Chloride → HCID 131727207, compound

HRID 1698381Notes

Reaction equation

HRID 1698381 reaction equation
[CH:1]1([Mg]Cl)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH3:9][Si:10]([O:13][CH3:14])(Cl)Cl.[Cl-].[NH4+]>C1COCC1>[CH:1]1([CH:9]([SiH2:10][O:13][CH3:14])[CH:1]2[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

5

Reactant 3

HCID 25517Ammonium ChlorideHCID 74580Dichloro(methoxy)methylsilaneHCID 178478990HCID 178478990, compound

Product 1

HCID 131727207HCID 131727207, compoundYield 80%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

The THF solution of cyclohexyl magnesium chloride as prepared above was added dropwise to the methylmethoxydichlorosilane solution obtained in Example 7, in the same manner as in Example 3(c), to effect the Grignard reaction. The post-treatment of the resulting Grignard reaction solution was carried out in the same manner as in Example 3(c), except that the saturated aqueous ammonium chloride solution used in Example 3(c), was used in a reduced amount of 80 ml instead of 120 ml. The organic layer was separated and was fractionally distilled under a reduced pressure, thereby to afford 39 g of dicyclohexylmethylmethoxysilane as a fraction boiling at 128° C.-129° C./7 mm Hg (yield; 80%).

Workup

  1. customthe Grignard reaction
  2. customThe post-treatment of the resulting Grignard reaction solution
  3. customThe organic layer was separated
  4. distillationwas fractionally distilled under a reduced pressure

Sources & evidence

ORD record
ord-df7a0f79ca5148299bd5758d25785260
Source dataset
uspto-grants-2012_04
Patent number
US08163950B2

Reaction notes

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