Tetrahydrofuran → (2-Chloro-4-phenylpyridin-3-yl)methanol

HRID 169856Notes

Reaction equation

HRID 169856 reaction equation
[Cl:1][c:2]1[c:3]([C:4](=[O:5])[OH:6])[c:7](-[c:11]2[cH:12][cH:13][cH:14][cH:15][cH:16]2)[cH:8][cH:9][n:10]1.[O:21]1[CH2:22][CH2:23][CH2:24][CH2:25]1.[S:17]([Cl:18])([Cl:19])=[O:20]>>[Cl:1][c:2]1[c:3]([CH2:4][OH:5])[c:7](-[c:11]2[cH:12][cH:13][cH:14][cH:15][cH:16]2)[cH:8][cH:9][n:10]1

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 24386Thionyl ChlorideHCID 183873122-Chloro-4-phenylnicotinic acid

Product 1

HCID 23089956(2-Chloro-4-phenylpyridin-3-yl)methanol

Sources & evidence

ORD record
ord-b1debcb3aac24b73802eb78b830179ef
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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