Triethylamine → HCID 70120094, compound

Participants

Reaction Conditions

Reaction Steps

To 1.07 g of N-(2,4-dichlorophenyl)-N-propylthiourea (Compound 10-1) in 6 ml of ethanol, there is added 1 ml of triethylamine followed, dropwise, by 1.3 g of 2-bromo-1-(2,4-dichlorophenyl)propan-1-one (Compound 1-1). The reaction mixture is heated for 3 hours at 78° C., it is evaporated to dryness and then the residue is taken up in dichloromethane. The organic phase is washed with water, dried over sodium sulphate and evaporated to dryness under vacuum.

Provenance & Evidence