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HRID1698880

反应详情

EQUATION

反应方程式

HRID 1698880 的结构方程式

REACTANTS

反应物

2
结构：[K+].[OH-]
HCID14797

Potassium hydroxide

HKO

结构：CCOC(=O)C(CC#CCNC(=O)OC(C)(C)C)(NC(C)=O)C(=O)OCC
HCID14561225

未命名化合物

PRODUCTS

生成物

1
结构：CCOC(=O)C(CC#CCNC(=O)OC(C)(C)C)(NC(C)=O)C(=O)O
HCID18322430

未命名化合物

收率 90%

AUXILIARIES

试剂、催化剂与溶剂

2
结构：CCO
溶剂HCID702

Ethanol

C2H6O

结构：O
溶剂HCID962

Water

H2O

PROCEDURE

实验过程

Ex-8e) Following the procedure described in Tetrahedron Lett Vol.21, 4263, (1980) partial saponification of 10.2 g of ethyl-2-acetylamino-6-t-butyloxycarbonylamino-2-ethoxycarbonyl-4-hexynoate is carried out in ethanol with 1.5 equivalent of KOH in water at 20-25° C. for 3 h to give 2-Acetylamino-6-t-butyloxycarbonylamino-2-ethoxycarbonyl-4-hexynoic acid in 90% yield.