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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 169906Generated: October 27, 2026

Hydrochloric Acid → 5-[2-(2,2,2-Trifluoro-1-hydroxy-ethyl)-phenyl]-pyridine-2-carbonitrile

https://huagongshe.com/reaction/169906

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantTetrahydrofuranHCID 8028—
ReactantTetrabutylammoniumHCID 16028—
ReactantFluoride IonHCID 28179—
Reactant(Trifluoromethyl)trimethylsilaneHCID 552549—
Reactant5-(2-Formylphenyl)picolinonitrileHCID 86621089—
Product5-[2-(2,2,2-Trifluoro-1-hydroxy-ethyl)-phenyl]-pyridine-2-carbonitrileHCID 66743510—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-f5248048263e4a65a0c52bcca5b428a2
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)