Hydrochloric Acid → 5-[2-(2,2,2-Trifluoro-1-hydroxy-ethyl)-phenyl]-pyridine-2-carbonitrile
Reaction equation
[CH2:44]1[O:45][CH2:46][CH2:47][CH2:48]1.[CH3:2][CH2:3][CH2:4][CH2:5][N+:6]([CH2:7][CH2:8][CH2:9][CH3:10])([CH2:11][CH2:12][CH2:13][CH3:14])[CH2:15][CH2:16][CH2:17][CH3:18].[CH:19](=[O:20])[c:21]1[c:22](-[c:27]2[cH:28][cH:29][c:30]([C:33]#[N:34])[n:31][cH:32]2)[cH:23][cH:24][cH:25][cH:26]1.[ClH:43].[F-:1].[F:35][C:36]([F:37])([F:38])[Si:39]([CH3:40])([CH3:41])[CH3:42]>>[CH:19]([OH:20])([c:21]1[c:22](-[c:27]2[cH:28][cH:29][c:30]([C:33]#[N:34])[n:31][cH:32]2)[cH:23][cH:24][cH:25][cH:26]1)[C:36]([F:35])([F:37])[F:38]Participants
7
Sources & evidence
- ORD record
- ord-f5248048263e4a65a0c52bcca5b428a2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
Loading…