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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1699119Generated: October 31, 2026

Isobutyronitrile → 5-chloro-2,2-dimethylpentanenitrile

https://huagongshe.com/reaction/1699119

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsobutyronitrileHCID 6559—
Reactant1-Bromo-3-chloropropaneHCID 8006—
Product5-chloro-2,2-dimethylpentanenitrileHCID 264217—

Reaction Steps

reacting isobutyronitrile with 1-bromo-3-chloropropane in the presence of a first base in a non-polar solvent at a temperature of about 15°to 65°C. to afford 5-chloro-2,2-dimethylpentanenitrile;

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06344580B1
Source datasetuspto-grants-2002_02
ORD IDord-78beef2858274801a207cbab4e15eac3
Source noteuspto-grants-2002_02