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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1699261Generated: October 29, 2026

1-Benzyl-4-piperidone → Hexahydro-1-methyl-4-[1-(phenylmethyl)-4-piperidinyl]-1H-1,4-diazepine

https://huagongshe.com/reaction/1699261

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Benzyl-4-piperidoneHCID 19220—
Reactant1-MethylhomopiperazineHCID 228349—
ProductHexahydro-1-methyl-4-[1-(phenylmethyl)-4-piperidinyl]-1H-1,4-diazepineHCID 1832116035%

Reaction Steps

Prepared analogously to Example A11a) from hexahydro-1-methyl-1H-1,4-diazepine and 1-(phenylmethyl)-4-piperidinone in a yield of 35% of theory. Colourless viscous oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06344449B1
Source datasetuspto-grants-2002_02
ORD IDord-59c724e2667049b29dee50a83eda4522
Source noteuspto-grants-2002_02