Morpholine → HCID 178484784, compound

HRID 1699408Notes

Reaction equation

HRID 1699408 reaction equation
[CH3:1][NH:2][C@H:3]1[CH2:8][CH2:7][C@H:6]([C:9]2[CH:14]=[CH:13][C:12]([CH2:15][N:16]3[CH2:21][CH2:20]O[CH2:18][CH2:17]3)=[CH:11][CH:10]=2)[CH2:5][CH2:4]1.[C:22]1(C2CCC(=O)CC2)C=CC=CC=1.N1CCOCC1.[O-2].[Al+3].[O-2].[O-2].[Al+3]>>[CH3:1][NH:2][C@H:3]1[CH2:8][CH2:7][C@H:6]([C:9]2[CH:14]=[CH:13][C:12]([CH2:15][N:16]3[CH2:21][CH2:20][CH2:22][CH2:18][CH2:17]3)=[CH:11][CH:10]=2)[CH2:5][CH2:4]1

Participants

5

Reactant 4

HCID 8083MorpholineHCID 786054-PhenylcyclohexanoneHCID 9989226AluminaHCID 178484785HCID 178484785, compound

Product 1

HCID 178484784HCID 178484784, compound

Procedure

cis/trans-N-methyl-4-[4-(morpholinomethyl)phenyl]cyclohexylamine, from 4-phenylcyclohexanone and morpholine; colourless solid; Rf values 0.26 and 0.48 (aluminium oxide, petroleum ether/ethyl acetate=5:1, v:v)

Sources & evidence

ORD record
ord-6ce0cab353494535b6d71b99e8ceceaa
Source dataset
uspto-grants-2002_02
Patent number
US06346545B1

Reaction notes

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