HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2-pyridylacetate → 4'-Cyanomethyl-2-(2-pyridyl)acetanilide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2-pyridylacetate | HCID 74264 | — |
| Reactant | 4-Aminophenylacetonitrile | HCID 77000 | — |
| Solvent | O-Xylene | HCID 7237 | — |
| Product | 4'-Cyanomethyl-2-(2-pyridyl)acetanilide | HCID 18319871 | 66.4% |
Reaction Steps
A reaction mixture of 5.12 g of methyl 2-pyridylacetate, 5.14 g of 4-aminobenzyl cyanide and 50 ml of xylene was heated to reflux for 24 hours. An appropriate amount of the solvent was evaporated, diethyl ether was added to the residue, and the resulting crystals were taken by filtration to give 5.65 g of 4′-cyanomethyl-2-(2-pyridyl)acetanilide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06346532B1 |
| Source dataset | uspto-grants-2002_02 |
| ORD ID | ord-95b5a1a61b7e4ac6a24934058bc63c39 |
| Source note | uspto-grants-2002_02 |