反应详情

A reaction mixture of 5.12 g of methyl 2-pyridylacetate, 5.14 g of 4-aminobenzyl cyanide and 50 ml of xylene was heated to reflux for 24 hours. An appropriate amount of the solvent was evaporated, diethyl ether was added to the residue, and the resulting crystals were taken by filtration to give 5.65 g of 4′-cyanomethyl-2-(2-pyridyl)acetanilide.

1. temperaturewas heated
2. temperatureto reflux for 24 hours
3. customAn appropriate amount of the solvent was evaporated
4. additiondiethyl ether was added to the residue
5. filtrationthe resulting crystals were taken by filtration