Potassium Hydroxide → HCID 54563878, compound

Participants

Reaction Steps

330 mg 6-(1-adamantoyloxy)-2-(1-adamantyl)-4H-chromen-4-one is dissolved in dioxane and treated with 5 ml of 10% aqueous potassium hydroxide solution. The mixture is stirred for 3 hours at room temperature and then poured into 2M aqueous pH 7 buffer solution. Extraction with ethyl acetate yields after drying and evaporation a crude product which is purified by chromatogaphy. The title compound is obtained [colourless crystals; mp 230°(from 2-propanol)].

Provenance & Evidence