反应详情

Another method is reported by Bhakuni et al. (Bhakuni R. S; Jain D. C and Sharma, R P., Indian J. Chemistry, 34B, 529-30 (1995). Arteether was prepared by dissolving dihydroartemisinin in alcohol and benzene mixture and then adding chlorotrimethylsilane as acid catalyst. The reaction was stirred for 2 hrs. at room temperature. The reaction mixture was washed with 10% sodium acetate solution and workup as usual method. The other products formed during the reaction were removed by column chromatography, to obtain pure arteether.

1. customArteether was prepared
2. customat room temperature
3. washThe reaction mixture was washed with 10% sodium acetate solution and workup as usual method
4. customThe other products formed during the reaction
5. customwere removed by column chromatography