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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1699771Generated: October 31, 2026

2-Fluoroanisole → 3'-Fluoro-2-(3-fluoro-4-methoxyphenyl)-4'-methoxyacetophenone

https://huagongshe.com/reaction/1699771

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-FluoroanisoleHCID 67576—
Reactant(3-Fluoro-4-methoxyphenyl)acetic acidHCID 521176—
Product3'-Fluoro-2-(3-fluoro-4-methoxyphenyl)-4'-methoxyacetophenoneHCID 1352637877.5%

Reaction Steps

Using 3-fluoro-4-methoxyphenylacetic acid and 2-fluoroanisole as starting materials, the procedures of Preparation Example 7 were repeated likewise, whereby the title compound was obtained in a yield of 77.5%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06348468B1
Source datasetuspto-grants-2002_02
ORD IDord-8883b50afb3941338f66cdcf644ebcd9
Source noteuspto-grants-2002_02