Benzylamine → HCID 17797533, compound

HRID 1699774Notes

Reaction equation

HRID 1699774 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:14]([C:15]3[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=3)=[N:13][N:12]([CH2:23][CH2:24][C:25]([OH:27])=O)[C:11](=[O:28])[CH:10]=2)=[CH:5][CH:4]=1.C(Cl)(=O)C(Cl)=O.[CH2:35]([NH2:42])[C:36]1[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=1>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:14]([C:15]3[CH:16]=[CH:17][C:18]([O:21][CH3:22])=[CH:19][CH:20]=3)=[N:13][N:12]([CH2:23][CH2:24][C:25]([NH:42][CH2:35][C:36]3[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=3)=[O:27])[C:11](=[O:28])[CH:10]=2)=[CH:5][CH:4]=1

Participants

4

Reactant 3

HCID 7504BenzylamineHCID 65578Oxalyl chlorideHCID 18369430HCID 18369430, compound

Product 1

HCID 17797533HCID 17797533, compoundYield 52.2%

Procedure

After 5,6-bis(4-methoxyphenyl)-2-(2-carboxyethyl)-2H-pyridazin-3-one was reacted with oxalyl chloride in a similar manner as in Example 113-(3), a further reaction was conducted with benzylamine, whereby the title compound was obtained in a yield of 52.2%.

Workup

  1. customa further reaction

Sources & evidence

ORD record
ord-679805b43d8b4b059d471f2b3a5826c2
Source dataset
uspto-grants-2002_02
Patent number
US06348468B1

Reaction notes

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