(Chloromethyl)cyclopropane → HCID 18369414, compound

HRID 1699791Notes

Reaction equation

HRID 1699791 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([C:10]2[C:15]([C:16]3[CH:21]=[CH:20][C:19]([O:22][CH3:23])=[C:18]([F:24])[CH:17]=3)=[N:14][NH:13][C:12](=[O:25])[CH:11]=2)[CH:5]=[CH:6][C:7]=1[O:8][CH3:9].Cl[CH2:27][CH:28]1[CH2:30][CH2:29]1>>[F:1][C:2]1[CH:3]=[C:4]([C:10]2[C:15]([C:16]3[CH:21]=[CH:20][C:19]([O:22][CH3:23])=[C:18]([F:24])[CH:17]=3)=[N:14][N:13]([CH2:27][CH:28]3[CH2:30][CH2:29]3)[C:12](=[O:25])[CH:11]=2)[CH:5]=[CH:6][C:7]=1[O:8][CH3:9]

Participants

3

Reactant 2

HCID 80013(Chloromethyl)cyclopropaneHCID 18369405HCID 18369405, compound

Product 1

HCID 18369414HCID 18369414, compound

Procedure

Using 5,6-bis(3-fluoro-4-methoxyphenyl)-2H-pyridazin-3-one and (chloromethyl)cyclopropane as starting materials, the procedures of Example 146 were repeated likewise, whereby the title compound was obtained quantitatively.

Sources & evidence

ORD record
ord-dfb6e05c14f243508ed364a595f5dfba
Source dataset
uspto-grants-2002_02
Patent number
US06348468B1

Reaction notes

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