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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1699817Generated: November 3, 2026

HCID 22388123, compound → 3H-Imidazo[4,5-b]pyridine-5-carbonitrile, 2-methyl-

https://huagongshe.com/reaction/1699817

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 22388123HCID 22388123—
ReactantHCID 22388467HCID 22388467—
Product3H-Imidazo[4,5-b]pyridine-5-carbonitrile, 2-methyl-HCID 22388136343.2%

Reaction Steps

In the same manner as in the following Preparation Example 14-2, 3-(1-bromonaphthalen-2-yl)methyl-2-methyl-3H-imidazo[4,5-b]pyridine-5-carbonitrile (139 mg) and 1-(1-bromo-naphthalen-2-yl)methyl-2-methyl-1H-imidazo[4,5-b]pyridine-5-carbonitrile (96 mg) were respectively obtained as pale-brown crystals and pale-brown amorphous from 2-methyl-1H-imidazo[4,5-b]pyridine-5-carbonitrile (200 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06348474B1
Source datasetuspto-grants-2002_02
ORD IDord-f9aa6ed391504cffaf1e00122be5f369
Source noteuspto-grants-2002_02