Hydrochloric Acid → HCID 22388387, compound

HRID 1699882Notes

Reaction equation

HRID 1699882 reaction equation
[C:1]([N:4]([CH2:17][C:18]1[CH:23]=[CH:22][C:21]([Cl:24])=[CH:20][C:19]=1[Cl:25])[C:5]1[CH:10]=[C:9]([C:11](=[O:13])[NH2:12])[CH:8]=[CH:7][C:6]=1[C:14](=[O:16])[NH2:15])(=O)[CH3:2].Cl>CO>[C:11]([C:9]1[CH:10]=[C:5]2[C:6]([C:14](=[O:16])[N:15]=[C:1]([CH3:2])[N:4]2[CH2:17][C:18]2[CH:23]=[CH:22][C:21]([Cl:24])=[CH:20][C:19]=2[Cl:25])=[CH:7][CH:8]=1)(=[O:13])[NH2:12]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 22388498HCID 22388498, compound

Product 1

HCID 22388387HCID 22388387, compoundYield 102.2%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

2-((N-Acetyl)-(2,4-dichlorobenzyl)amino)-1,4-dicarbamoylbenzene (1.50 g) in a mixture of concentrated hydrochloric acid (10 ml) and methanol (30 ml) was heated under reflux for 30 min. After concentration, the object compound (1.46 g) was obtained as white crystals.

Workup

  1. temperaturewas heated
  2. temperatureunder reflux for 30 min
  3. concentrationAfter concentration

Sources & evidence

ORD record
ord-9a62b363fd0f4b809f6535a3a6b42d4c
Source dataset
uspto-grants-2002_02
Patent number
US06348474B1

Reaction notes

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