Water → 6-Bromo-3-nitro-2-pyridinamine

HRID 1699932노트

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HRID 1699932 반응식
Br[C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][CH:5]=[C:4]([Br:11])[N:3]=1.[NH3:12].C(O)C.O>C(O)C>[NH2:12][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][CH:5]=[C:4]([Br:11])[N:3]=1

참가 물질

5

반응물 3

HCID 962WaterHCID 5550532,6-Dibromo-3-nitropyridineHCID 22020343Ethanol, reaction products with ammonia, distn. residues

생성물 1

HCID 120977456-Bromo-3-nitro-2-pyridinamine

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

To a suspension of 2,6-dibromo-3-nitropyridine (5.00 g) in ethanol (10 ml) was added an ammonia/ethanol solution (6.8 M, 15 ml) at room temperature, and the mixture was placed in a closed reaction vessel and stirred at room temperature for 19 hr. To the reaction mixture was added water (25 ml), and the precipitate was collected by filtration. The precipitate was washed with ethanol, suspended in ethanol (55 ml), heated and cooled. The precipitate was collected by filtration to give the objective compound (3.19 g) as a yellow powder.

후처리

  1. customthe mixture was placed in a closed reaction vessel
  2. filtrationthe precipitate was collected by filtration
  3. washThe precipitate was washed with ethanol
  4. temperatureheated
  5. temperaturecooled
  6. filtrationThe precipitate was collected by filtration

출처 및 근거

ORD 기록
ord-c3d8f595be464ebe82f597e2d58a0789
출처 데이터셋
uspto-grants-2002_02
특허 번호
US06348474B1

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