反应详情

A mixture of 3-cyanobenzaldehyde (2.0 g) and (triphenylphosphoranylidene) acetaldehyde (5.0 g) in 100 mL CH2Cl2 was stirred at reflux for 16 hours. The reaction was cooled, concentrated and purified on silica gel column (ethyl acetate/hexane=3/7) to afford 2.2 g of 3-cyano-1-(2-formylethenyl)benzene as a yellow oil.

1. temperatureat reflux for 16 hours
2. temperatureThe reaction was cooled
3. concentrationconcentrated
4. custompurified on silica gel column (ethyl acetate/hexane=3/7)