HuagongsheHuagongshe Chemistry Print Report · For research reference only
(Triphenylphosphoranylidene)acetaldehyde → 3-Cyano-1-(2-formylethenyl)benzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (Triphenylphosphoranylidene)acetaldehyde | HCID 75051 | — |
| Reactant | m-Formylbenzonitrile | HCID 90670 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 3-Cyano-1-(2-formylethenyl)benzene | HCID 54477214 | 91.8% |
Reaction Steps
A mixture of 3-cyanobenzaldehyde (2.0 g) and (triphenylphosphoranylidene) acetaldehyde (5.0 g) in 100 mL CH2Cl2 was stirred at reflux for 16 hours. The reaction was cooled, concentrated and purified on silica gel column (ethyl acetate/hexane=3/7) to afford 2.2 g of 3-cyano-1-(2-formylethenyl)benzene as a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06350761B1 |
| Source dataset | uspto-grants-2002_02 |
| ORD ID | ord-302567ddfded4a23971f0fe358d863fc |
| Source note | uspto-grants-2002_02 |