Potassium Carbonate → HCID 18318196, compound

Participants

Reaction Conditions

Reaction Steps

To 4-(N′-(t-butoxycarbonyl)piperidin-4-yl)oxy-3-nitro-N-(trifluoromethylcarbonyl)benzenamine in methanol (150 mL) and water (150 mL) was added K2CO3 (6.0 g) and the reaction was heated to 50° C. for overnight. The reaction was extracted with ethyl acetate. The extract was dried, concentrated and purified on silica gel column (ethyl acetate/hexane) to afford 4-(N′-(t-butoxycarbonyl)piperidin-4-yl)oxy-3-nitrobenzenamine (11.0 g).

Provenance & Evidence