反应详情

193 mg (0.568 mmol) of 2-acetyl-3-(3-chlorophenyl)-N-(3-phenyl-2-propene-1-yl)acrylamide and 87.6 mg (0.568 mmol) of 2-cyanoethyl 3-aminocrotonate were heated at 70° C. under stirring in 2.8 ml of 2-propanol overnight. 2-Propanol was evaporated under reduced pressure. The residue was purified by the silica gel chromatography (hexane/ethyl acetate=1/2) to obtain the title compound.

1. custom2-Propanol was evaporated under reduced pressure
2. customThe residue was purified by the silica gel chromatography (hexane/ethyl acetate=1/2)