Sodium Hydroxide → HCID 70155777, compound

Participants

Reaction Steps

134 mg (1.16 mmol) of 5-(2-cyanoethyl) 4-(3-chlorophenyl)-2-dimethoxymethyl-6-methyl-3-(3-phenyl-2-propene-1-ylcarbamoyl)-1,4-dihydropyridine-5-carboxylate was dissolved in 2.5 ml of methanol. 0.25 ml of 1 N aqueous sodium hydroxide solution was added to the obtained solution, and they were stirred at room temperature for 3 hours. An aqueous potassium hydrogensulfate solution was added to the reaction mixture. After the solvent was evaporated under reduced pressure, the residue was washed with water and then dried under reduced pressure to obtain the title compound.

Provenance & Evidence