反应详情

温度

50 °C

A suspension of 1 g of the compound of Example 1 in 15 ml of water, 30 ml of ethanol and 5 ml of 1 M sodium hydroxide solution is heated at 50° C. for 10 hours. The reaction mixture is then cooled and 5 ml of 1M HCl are added. The resulting precipitate is suction-filtered off, washed with water and then dried in vacuo, enabling the expected product to be isolated.

1. temperatureThe reaction mixture is then cooled
2. filtrationThe resulting precipitate is suction-filtered off
3. washwashed with water
4. customdried in vacuo
5. customto be isolated