反应详情

温度

260 °C

A mixture of 2,2-dimethyl-5-[(3-oxo-5-(2-chlorophenyl)-1-cyclohexenylamino)methylene]-[1,3]dioxane-4,6-dione (1.6 g) in diphenylether (20 ml) was stirred at 260° C. for 30 minutes. Under reduced pressure, the solvent was evaporated, and the resulting crystals were washed with petroleum ether and recrystallized from ethanol to give 7-(2-chlorophenyl)-1,4,5,6,7,8-hexahydroquinoline-4,5-dione (1.1 g).

1. customUnder reduced pressure, the solvent was evaporated
2. washthe resulting crystals were washed with petroleum ether
3. customrecrystallized from ethanol