HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 178424165, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 4-Methyl-7-(2-methylphenyl)-5-oxo-cyclopenta[2,1-b]pyridine | HCID 18317297 | — |
| Reactant | HCID 178418668 | HCID 178418668 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178424165 | HCID 178424165 | 71.8% |
Reaction Steps
A mixture of 4-methyl-7-(2-methylphenyl)-5-oxo-cyclopenta[2,1-b]pyridine (48 mg), aminoguanidine hydrochloride (25 mg) and concentrated hydrochloric acid (40 mg) in ethanol (1 ml) was refluxed for 2 hours. The reaction solution was cooled, and precipitated crystals were filtered, washed with ethanol and dried to give 5-guanidinoimino-4-methyl-7-(2-methylphenyl)cyclopenta[2,1-b]pyridine hydrochloride (Compound 91) (48 mg) as yellow crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06350749B1 |
| Source dataset | uspto-grants-2002_02 |
| ORD ID | ord-48ef27a0bc3d405cb74fed725068992e |
| Source note | uspto-grants-2002_02 |